What is a Certificate of Analysis (COA)?

A Certificate of Analysis (COA) is a document from an accredited analytical laboratory confirming a compound's identity, purity, and potency. For research peptides it typically includes HPLC chromatograms and mass spectrometry data. Independent third-party COAs are the gold standard for verifying compound quality.

A Certificate of Analysis is a document issued by an accredited analytical laboratory confirming the identity, purity, and potency of a synthesized compound. For research peptides, a COA typically includes HPLC chromatograms, mass spectrometry data, amino acid composition analysis, and solubility data. Independent third-party COAs — generated by labs with no financial relationship to the supplier — are considered the gold standard for verifying compound quality in preclinical research.

Source: USP General Chapter ⟨1058⟩ · PubMed

Summarised from peer-reviewed literature for research reference. For laboratory research use only.