How does AOD-9604 differ from full-length growth hormone in its metabolic effects?

AOD-9604 is a synthetic analog of the C-terminal fragment (residues 177–191) of human growth hormone, modified with a tyrosine at the N-terminus. Unlike full-length hGH, AOD-9604 does not bind the growth hormone receptor or stimulate IGF-1 production, meaning it does not produce the anabolic, hyperglycemic, or epiphyseal effects of exogenous GH. Research has focused on its interaction with beta-adrenergic receptors in adipose tissue as a potential mechanism for selective lipolysis. Animal studies have demonstrated fat-mobilizing activity without the metabolic side effects associated with intact GH.

Source: Mol Cell Endocrinol (2001) · PubMed

AOD-9604 — 5mg, 99.5% purity →

Summarised from peer-reviewed literature for research reference. For laboratory research use only.